Evidence· July 9, 2026 · 16 min readBenzodiazepines in FAERS: Adverse Events, Dependence, and Safety SignalsA pharmacovigilance cut of 716,126 benzodiazepine FAERS reports, analyzing drug-safety leaders, serious and fatal outcomes, and FDA...By Ran Chen#Real-World Evidence#Label Warnings#Boxed Warning
Pipeline· July 1, 2026 · 19 min readCentanafadine PDUFA July 24, 2026: Pipeline and Access for Otsuka's NDSRIOtsuka's centanafadine PDUFA target date is July 24, 2026. A review of Phase 3 trials, non-stimulant mechanisms, and payer access...By Ran Chen#PDUFA Date#Priority Review#CNS and Migraine
Generics· June 26, 2026 · 21 min readGeneric Tecfidera: Dimethyl Fumarate Patent Settlements and NADAC ErosionA regulatory and pricing analysis of generic Tecfidera (dimethyl fumarate), detailing the Orange Book landscape, CMS NADAC price...By Ran Chen#Generics#Orange Book#PBM
Pricing & Access· May 25, 2026 · 9 min readCGRP inhibitor access landscape: eight drugs, coverage, and payer criteria in 2026Cross-CGRP coverage guide for Aimovig, Emgality, Ajovy, Nurtec ODT, Qulipta, Ubrelvy, Vyepti, and Zavzpret. Formulary tiers, PA...By Ran Chen#CGRP#CNS and Migraine#Coverage Access